Smoking can causes asthma in third generationPublished On: Tue, Oct 30th, 2012 | Addiction | By IANS
The dangers of smoking on users and their children are known but new researchdemonstrates that it also can causes asthma in their grandchildren.
Asthma is a major public health problem. It is the most common chronic disease of childhood. While there are many factors which contribute to asthma – maternal smoking during pregnancy is a well known, and avoidable, risk.
During pregnancy nicotine can affect a developing foetus’ lungs, predisposing the infant to childhood asthma.
Exposure inside the uterus resulted in both male and female offspring having reduced lung function consistent with asthma.
It also impaired lung function of their own offspring, even though the first generation rats were not themselves exposed to nicotine once they were born, according to an UCLA statement.
Levels of proteins increased by maternal smoking in the lungs of their offspring such as fibronectin, collagen and nicotinic aceylcholine receptors, were also found to be raised in the grandchildren.