Tuesday 02 September, 2014

Diet leads BPA to accumulate faster than previously thought

Published On: Mon, Jun 6th, 2011 | Biochemistry | By BioNews

A new University of Missouri study has showed that the exposure to the controversial chemical Bisphenol A (BPA) through diet has been underestimated by previous lab tests, as it accumulates more rapidly within the body than it was previously thought.

In the study, researchers gave a set of mice a steady diet, supplemented with BPA throughout the day, and compared BPA concentrations in them, and found an increased absorption and accumulation of the substance in their blood.

“People are primarily and unknowingly exposed to BPA through the diet because of the various plastic and paper containers used to store our food are formulated with BPA,” said the study’s lead author Cheryl Rosenfeld, associate professor in biomedical sciences and Bond Life Sciences investigator.

“We know that the active form of BPA binds to our steroid receptors, meaning it can affect estrogen, thyroid and testosterone function. It might also cause genetic mutations. Thus, this chemical can hinder our ability to reproduce and possibly cause behavioral abnormalities that we are just beginning to understand,” he said.

“We believe that these mouse model studies where the BPA exposure is through the diet is a more accurate representation of what happens to BPA as the human body attempts to processes this toxic substance,” said Rosenfeld,” he added.

The study is published in Environmental Health Perspectives.

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